I just tried on an up-to-date 18.2 and up-to-date 18 box, both of which work fine with the binary package...
I also tried on the virtual machine with 18 which I used to build the package. There, evaluation of a cell makes the GUI hang (does not respond to e.g. selecting a menu). After about 10-15 seconds, it eventually comes back to life, displaying the output, but the spinner keeps turning. Is this what you see as well?
It sounds like there is an issue with the client-to-server network connection. It is conceivable that it has something to do with some subtle ipv4 versus ipv6 issues in the network layer.